Doubts arise on their usage and the protection against the virus, with the arrival of new vaccines against covid-19. The fear lies in the side effects that have been reported gradually after vaccination. However, in preliminary clinical trials, they did not detect. This article will introduce you to the most critical aspects of the coronavirus vaccine developed by Janssen, a Johnson & Johnson and Moderna subsidiary.
According to CDC, on April 23, 2021, authorized Janssen’s JNJ-78436735 vaccine was. It stands out from those existing in the anticovid biologics market for being single-dose; that is; only one dose is sufficient to generate antibodies against the virus. In addition, recent scientific evidence presented by the company confirms the ability to respond to the Delta variant. This Sars-CoV-2 mutation looks like having more resistance to current vaccines and has a high contagion capacity.
The Official statements read, “each dose of Johnson & Johnson’s covid-19 vaccine generated neutralizing antibodies against several variants of interest. It has increased over time. Even against the Beta variant (B.1.351), the Delta variant (B.1 .617.2), somewhat resistant to neutralization, the Gamma variants (P.1) and others, including the Alpha (B.1.1.7), Kappa (B.1.617.1), Epsilon variants (B.1.429) and D614G, as well as the original strain of SARS-CoV-2 (WA1 / 2020).”
Other data of interest provided by the CDC indicate that this vaccine was 66.3% effective in clinical trials to prevent covid-19. “People reached the maximum possible protection two weeks after being vaccinated,” highlights the US health authority. With this above, it is essential to consider that some of the participants in these trials suffered from some of the risk comorbidities for covid-19: obesity (28.7%), hypertension (10.2%), type 2 diabetes ( 7.3%) and HIV infection (2.7%).
Two biological doses provide Immunity to the virus. As for Moderna’s vaccine, mRNA-1273, the US health authorities recommend its use in people over 18 years of age. According to evidence from clinical trials, that must be applied in 28 days that rate its effectiveness at 94.1%. But, if one talks about the efficacy against the Delta variant, recent research by the pharmaceutical company confirms that it provides safety to vaccinated individuals, although its protection capacity is low.
Moderna created the biological works with mRNA (messenger RNA) technology, Like the Pfizer vaccine. So it is not developed with any part of the virus and therefore cannot cause Sars-CoV-2 infection. So far, scientists do not know how long immunity to the Coronavirus lasts with Moderna’s drug. However, the pharmaceutical company assured that a study is underway to determine this information.
Side effects of Janssen and Moderna Vaccines
According to ‘Our World in Data, 24.6% of the world’s population has received at least one dose of anticovid vaccines. Institutions have administered 3.290 million doses worldwide, and of which used each day is 34.18 million. Health authorities, including WHO and FDA, have assured the general population that side effects can occur after receiving the Janssen and Moderna Vaccines against covid-19 with a duration of 2 to 5 days.
As per the updated information, the Janssen and Moderna vaccines are painful in the applied area. Muscle pain, chills, fever, reddishness, swelling, tiredness, headache, and nausea are the most common side effects.
If you faced any of the following symptoms, seek immediate medical attention:
- Shortness of breath
- Chest pain
- Leg swelling
- Persistent abdominal pain
- Wounding or small spots of blood under the skin at the injection site
- Severe or persistent headaches or blurred vision
Reports confirm that the most common side effects in people between the ages of 18 and 59.
If you faced any of the following symptoms, you require immediate medical attention:
- Difficulty breathing
- Swelling of the face and throat
- Fast heartbeat
- Severe skin rash all over the body
- Dizziness and weakness
- Chest pain
- Shortness of breath
- Sensation racing, shaking, or pounding heart
With the Janssen vaccine, the US health authorities have reported fainting episodes during the recommended wait after vaccination among side effects. However, it is not yet clear whether these syncopes are a direct consequence of immunization or whether they respond to a particular condition of individuals before being vaccinated.
Similarly, People concerned have documented a plausible causal relationship between the Janssen vaccine and thrombosis-thrombocytopenia syndrome or TTS. The prevalence rate is 7 per 1 million vaccinated women between 18 and 49 years of age and occurs less frequently in women 50 years and older and men of any age. Medicos recommend Monitoring for symptoms after vaccination in women immunized with Janssen and younger than 50 years.
Compared to Moderna’s vaccine, the most severe effects reported have been inflammation of the heart muscle and inflammation of the heart’s outer lining. It has occurred in very few cases. However, doctors noticed most of the cases in young people. That appears more often after applying the second dose. It should note that the Concerned have recorded these adverse events in all mRNA vaccines. That is, People have also registered in vaccinated with Pfizer-BioNTech.
In Colombia, People are using the Janssen vaccine mainly to immunize the inhabitants of hard-to-reach territories. For its part, Moderna’s vaccine received the ASUE on June 25.